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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR3C1 All Species: 21.52
Human Site: S616 Identified Species: 52.59
UniProt: P04150 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04150 NP_000167.1 777 85659 S616 G W R S Y R Q S S A N L L C F
Chimpanzee Pan troglodytes A7X8B3 933 98902 V771 G W R S Y K H V S G Q M L Y F
Rhesus Macaque Macaca mulatta XP_001097126 777 85480 S616 G W R S Y R Q S S A N L L C F
Dog Lupus familis XP_535225 780 85853 S619 G W R S Y R Q S S G S M L C F
Cat Felis silvestris
Mouse Mus musculus P06537 783 86034 A622 G W R S Y R Q A S G N L L C F
Rat Rattus norvegicus P06536 795 87538 S634 G W R S Y R Q S S G N L L C F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510749 775 84527 S614 G W R S Y K Q S S A N L L C F
Chicken Gallus gallus P07812 786 85725 V624 G W R S Y K H V S G Q M L Y F
Frog Xenopus laevis P49844 776 84959 T615 G W R S Y K Q T N G S I L Y F
Zebra Danio Brachydanio rerio NP_001018547 746 81903 G587 R S Y Q H C N G N M L C F A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 98.3 93 N.A. 89.5 88.4 N.A. 82.6 34.4 63.3 48.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 47.7 98.9 96.2 N.A. 93.7 92 N.A. 90.2 47.8 77.3 64.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 80 N.A. 86.6 93.3 N.A. 93.3 53.3 53.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 93.3 N.A. 93.3 93.3 N.A. 100 66.6 86.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 30 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 10 0 60 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 90 % F
% Gly: 90 0 0 0 0 0 0 10 0 60 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 20 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 50 90 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 30 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 20 0 50 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 10 0 0 70 0 0 0 20 0 0 0 0 % Q
% Arg: 10 0 90 0 0 50 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 90 0 0 0 50 80 0 20 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % V
% Trp: 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 90 0 0 0 0 0 0 0 0 30 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _